Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1,471
Tocris Bioscience™ Sunitinib malate
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CAS: 341031-54-7 Molecular Formula: C26H33FN4O7
| CAS | 341031-54-7 |
|---|---|
| Molecular Formula | C26H33FN4O7 |
1,472
Tocris Bioscience™ 1-Oleoyl lysophosphatidic acid sodium salt
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CAS: 325465-93-8 Molecular Formula: C21H40NaO7P
| CAS | 325465-93-8 |
|---|---|
| Molecular Formula | C21H40NaO7P |
1,473
Tocris Bioscience™ Aripiprazole
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High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist
1,474
Tocris Bioscience™ MI 2 (MALT1 inhibitor)
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CAS: 1047953-91-2 Molecular Formula: C19H17Cl3N4O3
| CAS | 1047953-91-2 |
|---|---|
| Molecular Formula | C19H17Cl3N4O3 |
1,475
Tocris Bioscience™ NVS-STG2
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STING agonist, molecular glue that causes oligomerization of STING
| Target | STING Agonists |
|---|---|
| CAS | 3030588-01-0 |
| Purity | 0.98 |
| Chemical Name or Material | 4-((4-(2-(tert-Butyl)-5,5-dimethyl-1,3-dioxan-2-yl)benzyl)amino)-3-methoxybenzoic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H33NO5 |
1,476
Tocris Bioscience™ MR 24
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Potent and selective MST3 kinase binding inhibitor
| Target | Other Kinase Inhibitors |
|---|---|
| Purity | 0.98 |
| Chemical Name or Material | 8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H29ClN6O3.3HCl |
1,477
Tocris Bioscience™ VU 0422288
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Selective group III mGlu positive allosteric modulator
| CAS | 1630936-95-6 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | VU 0422288 |
| Recommended Storage | Store at 4°C |
| Synonym | N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide |
| Molecular Formula | C17H11Cl2N3O2 |
| Formula Weight | 360.19 |
1,478
Tocris Bioscience™ trans-ISRIB
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Integrated stress response (ISR) inhibitor
| Inhibitors | trans-ISRIB |
|---|---|
| Product Type | trans-ISRIB |
| Molecular Weight (g/mol) | 451.34 |
| Purity | >99% |
1,479
Tocris Bioscience™ Zonisamide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 68291-97-4 Molecular Formula: C8H8N2O3S
| CAS | 68291-97-4 |
|---|---|
| Molecular Formula | C8H8N2O3S |
1,480
Tocris Bioscience™ CHR 6494 trifluoroacetate
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Potent and selective haspin inhibitor
1,481
Tocris Bioscience™ (S)-PFI 2 hydrochloride
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Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)
1,482
Tocris Bioscience™ Trovafloxacin mesylate
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CAS: 147059-75-4 Molecular Formula: C21H19F3N4O6S
| CAS | 147059-75-4 |
|---|---|
| Molecular Formula | C21H19F3N4O6S |
1,483
Tocris Bioscience™ W 54011
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High affinity C5a receptor antagonist
| Target | Complement Signaling inhibitors |
|---|---|
| CAS | 405098-33-1 |
| Purity | >98% |
| Chemical Name or Material | N-[[4-(Dimethylamino)phenyl]methyl]-1,2,3,4-tetrahydro-7-methoxy-N-[4-(1-methylethyl)phenyl]-1-naphthalenecarboxamide hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C30H36N2O2.HCl |
| Formula Weight | 493.08 |
1,484
Tocris Bioscience™ (S)-Duloxetine hydrochloride
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CAS: 136434-34-9 Molecular Formula: C18H20ClNOS
| CAS | 136434-34-9 |
|---|---|
| Molecular Formula | C18H20ClNOS |
1,485
Tocris Bioscience™ Zileuton
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CAS: 111406-87-2 Molecular Formula: C11H12N2O2S
| CAS | 111406-87-2 |
|---|---|
| Molecular Formula | C11H12N2O2S |